Latest papers

Structures of respiratory syncytial virus nucleocapsid protein from two crystal forms: details of potential packing interactions in the native helical form.

Structure of PA4019, a putative aromatic acid decarboxylase from Pseudomonas aeruginosa.

Substrate binding of a GH5 endoglucanase from the ruminal fungus Piromyces rhizinflata.

A structural model of the Sgt2 protein and its interactions with chaperones and the Get4/Get5 complex.

Structures and oxygen affinities of crystalline human hemoglobin C (β6 Glu-Lys) in the R and R2 quaternary structures.

NrdH-redoxin protein mediates high enzyme activity in manganese-reconstituted ribonucleotide reductase from Bacillus anthracis.

CD1b tetramers bind αβ T cell receptors to identify a mycobacterial glycolipid-reactive T cell repertoire in humans.

Cutting Edge: Structural basis for the recognition of β-linked glycolipid antigens by invariant NKT cells.

Structural basis of simultaneous recruitment of the transcriptional regulators LMO2 and FOG1/ZFPM1 by the transcription factor GATA1.

Neuronal circuitry regulates the response of Caenorhabditis elegans to misfolded proteins.

High-speed atomic force microscopy reveals rotary catalysis of rotorless F₁-ATPase.

Biochemistry. Seeing a molecular motor at work.

Oligomeric Structure of the Chemokine CCL5/RANTES from NMR, MS, and SAXS Data

Crystal structure of reovirus attachment protein σ1 in complex with sialylated oligosaccharides.

Crystal structure of PrgI-SipD: insight into a secretion competent state of the type three secretion system needle tip and its interaction with host ligands.

Recessive mutations in KCNJ13, encoding an inwardly rectifying potassium channel subunit, cause leber congenital amaurosis.

Structural basis of chemokine sequestration by CrmD, a poxvirus-encoded tumor necrosis factor receptor.

Crystallography of a Lewis-binding norovirus, elucidation of strain-specificity to the polymorphic human histo-blood group antigens.

Dynein struts its stuff. AD - National Heart, Lung, and Blood Institute, U.S. National Institutes of Health, Bethesda, Maryland, USA. sellersj@nhlbi.nih.gov FAU - Billington, Neil AU - Billington N FAU - Sellers, James R AU - Sellers JR LA - eng PT - Journal Article PL - United States TA - Nat Struct Mol Biol JT - Nature structural & molecular biology JID - 101186374 RN - EC 3.6.4.2 (Dyneins) SB - IM MHDA- 2011/06/21 06:00 AID - nsmb.2082 [pii] AID - 10.1038/nsmb.2082 [doi] PST - ppublish SO - Nat Struct Mol Biol. 2011 Jun;18(6):635-6.

In search of the protein native state with a probabilistic sampling approach.