Latest papers

Structural analysis of a holoenzyme complex of mouse dihydrofolate reductase with NADPH and a ternary complex with the potent and selective inhibitor 2,4-diamino-6-(2'-hydroxydibenz[b,f]azepin-5-yl)methylpteridine.

Metal trafficking for nitrogen fixation: NifQ donates molybdenum to NifEN/NifH for the biosynthesis of the nitrogenase FeMo-cofactor.

A newly discovered role for iron-sulfur clusters.

Reduction of drosopterin content caused by a 45-nt insertion in Henna pre-mRNA of Drosophila melanogaster.

Metal complexes with the ligand derived from 6-acetyl-1,3,7-trimethyllumazine and benzohydrazide. Molecular structures of two new Co(II) and Rh(III) complexes and analysis of in vitro antitumor activity.

Structure of a putative molybdenum-cofactor biosynthesis protein C (MoaC) from Sulfolobus tokodaii (ST0472).

The sulfurtransferase activity of Uba4 presents a link between ubiquitin-like protein conjugation and activation of sulfur carrier proteins.

Splice-specific functions of gephyrin in molybdenum cofactor biosynthesis.

Molybdoproteomes and evolution of molybdenum utilization.

Evolutionary persistence of the molybdopyranopterin-containing sulfite oxidase protein fold.

[Structure and mechanism of molybdenum hydroxylase]

Anticancer photodynamic and non-photodynamic effects of pterin derivatives on a pancreatic cancer cell line.

A widespread riboswitch candidate that controls bacterial genes involved in molybdenum cofactor and tungsten cofactor metabolism.

Inhibitors of the molybdenum cofactor containing 4-hydroxybenzoyl-CoA reductase.

Role of mammalian cytosolic molybdenum Fe-S flavin hydroxylases in hepatic injury.

Discovery of potent pteridine reductase inhibitors to guide antiparasite drug development.

Versatile coordinative abilities of a new hybrid pteridine-thiosemicarbazone ligand: crystal structure, spectroscopic characterization, and luminescent properties.

Binding mode analysis of 2,4-diamino-5-methyl-5-deaza-6-substituted pteridines with Mycobacterium tuberculosis and human dihydrofolate reductases.

Function of MoaB proteins in the biosynthesis of the molybdenum and tungsten cofactors.

Crystal structure of a molybdopterin synthase-precursor Z complex: insight into its sulfur transfer mechanism and its role in molybdenum cofactor deficiency.