Latest papers

Two pyranocoumarins from the seeds of Calophyllum polyanthum.

[Progress in HIV non-nucleoside reverse transcriptase inhibitors (NNRTIs)].

Pyranocoumarin(+/-)-4'-O-acetyl-3'-O-angeloyl-cis-khellactone induces mitochondrial-dependent apoptosis in HL-60 cells.

Concise synthesis of anti-HIV-1 active (+)-inophyllum B and (+)-calanolide A by application of (-)-quinine-catalyzed intramolecular oxo-Michael addition.

Anti-HIV natural product (+)-calanolide A is active against both drug-susceptible and drug-resistant strains of Mycobacterium tuberculosis

Recent advances in the development of next generation non-nucleoside reverse transcriptase inhibitors.

Reversal of multidrug resistance in cancer cells by pyranocoumarins isolated from Radix Peucedani.

Inocalophyllins A, B and their methyl esters from the seeds of Calophyllum inophyllum.

Pyranocoumarins isolated from Peucedanum praeruptorum as differentiation inducers in human leukemic HL-60 cells.

Mechanisms of relaxant action of a pyranocoumarin from Peucedanum japonicum in isolated rat thoracic aorta.

Safety and pharmacokinetic profile of multiple escalating doses of (+)-calanolide A, a naturally occurring nonnucleoside reverse transcriptase inhibitor, in healthy HIV-negative volunteers.

Safety and pharmacokinetics of single doses of (+)-calanolide a, a novel, naturally occurring nonnucleoside reverse transcriptase inhibitor, in healthy, human immunodeficiency virus-negative human subjects.

Anti-HIV-1 activity of calanolides used in combination with other mechanistically diverse inhibitors of HIV-1 replication.

Quantification of (+)-calanolide A, a novel and naturally occurring anti-HIV agent, by high-performance liquid chromatography in plasma from rat, dog and human.

Calanolide looks promising.

Plant-derived and semi-synthetic calanolide compounds with in vitro activity against both human immunodeficiency virus type 1 and human cytomegalovirus.

Unique anti-human immunodeficiency virus activities of the nonnucleoside reverse transcriptase inhibitors calanolide A, costatolide, and dihydrocostatolide.

Calanolide A: a natural non-nucleoside reverse transcriptase inhibitor.

In vivo anti-HIV activity of (+)-calanolide A in the hollow fiber mouse model.

Pharmaceutical properties of related calanolide compounds with activity against human immunodeficiency virus.