Latest papers

Aqueous penetration of moxifloxacin 0.5% ophthalmic solution and besifloxacin 0.6% ophthalmic suspension in cataract surgery patients.

Ultrasound protocols to measure carotid intima-media thickness in trials; comparison of reproducibility, rate of progression, and effect of intervention in subjects with familial hypercholesterolemia and subjects with mixed dyslipidemia.

[Dermatopharmacokinetic studies of liangfu cream in mice skin].

In vitro anticancer screening and radiosensitizing evaluation of some new quinolines and pyrimido[4,5-b]quinolines bearing a sulfonamide moiety.

Beneficial direct adipotropic actions of pitavastatin in vitro and their manifestations in obese mice.

Two new aurachins from Rhodococcus sp. Acta 2259. AD - Institut fur Chemie, Technische Universitat Berlin, Berlin, Germany. FAU - Nachtigall, Jonny AU - Nachtigall J FAU - Schneider, Kathrin AU - Schneider K FAU - Nicholson, Graeme AU - Nicholson G FAU - Goodfellow, Michael AU - Goodfellow M FAU - Zinecker, Heidi AU - Zinecker H FAU - Imhoff, Johannes F AU - Imhoff JF FAU - Sussmuth, Roderich D AU - Sussmuth RD FAU - Fiedler, Hans-Peter AU - Fiedler HP LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20100707 PL - Japan TA - J Antibiot (Tokyo) JT - The Journal of antibiotics JID - 0151115 RN - 0 (DNA, Bacterial) RN - 0 (DNA, Ribosomal) RN - 0 (Enzyme Inhibitors) RN - 0 (Quinolines) RN - 0 (RNA, Ribosomal, 16S) RN - 0 (Sewage) RN - EC 2.7.11.1 (glycogen synthase kinase 3 beta) RN - EC 2.7.11.26 (Glycogen Synthase Kinase 3) SB - IM MHDA- 2010/10/14 06:00 PHST- 2010/07/07 [aheadofprint] AID - ja201079 [pii] AID - 10.1038/ja.2010.79 [doi] PST - ppublish SO - J Antibiot (Tokyo). 2010 Sep;63(9):567-9. Epub 2010 Jul 7.

Interaction of gatifloxacin with efflux transporters: a possible mechanism for drug resistance.

Signaling via GPR30 protects the myocardium from ischemia/reperfusion injury.

Clinical efficacy of moxifloxacin versus comparator therapies for community-acquired pneumonia caused by Legionella spp.

Pharmacodynamics of moxifloxacin versus vancomycin against biofilms of methicillin-resistant Staphylococcus aureus and epidermidis in an in vitro model.

New quinoline derivatives: synthesis and investigation of antibacterial and antituberculosis properties.

New antituberculous drugs in development.

Double-blind, controlled phase II study of a 5-HT6 receptor antagonist, SB-742457, in Alzheimer's disease.

Prevention of Escherichia coli K1 penetration of the blood-brain barrier by counteracting the host cell receptor and signaling molecule involved in E. coli invasion of human brain microvascular endothelial cells.

Cholecystokinin/Cholecystokinin-1 receptor-mediated peripheral activation of the afferent vagus by enteral nutrients attenuates inflammation in rats.

Compensatory activation of Akt in response to mTOR and Raf inhibitors - a rationale for dual-targeted therapy approaches in neuroendocrine tumor disease.

Mechanisms underlying off-target effects of the cholesteryl ester transfer protein inhibitor torcetrapib involve L-type calcium channels.

Is a blood pressure rise the only deleterious off-target effect of cholesterol ester transfer protein inhibitors?

Severe corneal changes following intravitreal injection of bevacizumab.

A small-molecule oxocarbazate inhibitor of human cathepsin L blocks severe acute respiratory syndrome and ebola pseudotype virus infection into human embryonic kidney 293T cells.