Latest papers

Protein-facilitated folding of group II intron ribozymes.

[Construction of GCV-specific hammerhead ribozyme recombinant vector of pyruvate kinase in Giardia lamblia].

Involvement of 1,25D3-MARRS (membrane associated, rapid response steroid-binding), a novel vitamin D receptor, in growth inhibition of breast cancer cells.

The emergence of ribozymes synthesizing membrane components in RNA-based protocells.

Multiple native states reveal persistent ruggedness of an RNA folding landscape.

Extracellular production of an RNA aptamer by ribonuclease-free marine bacteria harboring engineered plasmids: a proposal for industrial RNA drug production.

Autocatalysis and organocatalysis with synthetic structures.

RNA as a drug target: recent patents on the catalytic activity of trans-splicing ribozymes derived from group I intron RNA.

The application of ribozymes and DNAzymes in muscle and brain.

Shaping RNA structures with metal ions and metal ion complexes.

Knocking down gene expression with dendritic vectors.

Quantifying the relationship between sequence and three-dimensional structure conservation in RNA

Hammerhead ribozymes: true metal or nucleobase catalysis? Where is the catalytic power from?

RNA therapeutics: function, design, and delivery. Preface.

Design principles for ligand-sensing, conformation-switching ribozymes.

The identity of the nucleophile substitution may influence metal interactions with the cleavage site of the minimal hammerhead ribozyme.

Conditional RNA interference mediated by allosteric ribozyme.

Ribozyme to TGF-beta1 mRNA abrogates immunosuppressive effects of human colorectal adenocarcinoma HRT-18 cells in vitro and in vivo.

Efficient Knockdown of Human prnp mRNA Expression Levels Using Hybrid Hammerhead Ribozymes

Identification and characterization of a highly efficient anti-HIV pol hammerhead ribozyme.