Latest papers

PBX1 Genomic Pioneer Function Drives ERα Signaling Underlying Progression in Breast Cancer.

A switch between cytoprotective and cytotoxic autophagy in the radiosensitization of breast tumor cells by chloroquine and vitamin D.

Akt determines cell fate through inhibition of the PERK-eIF2α phosphorylation pathway.

Exploiting cancer cell vulnerabilities to develop a combination therapy for ras-driven tumors.

Lung cancer signatures in plasma based on proteome profiling of mouse tumor models. LID - 10.1016/j.ccr.2011.08.007 [doi]

Tumor entrained neutrophils inhibit seeding in the premetastatic lung. LID - 10.1016/j.ccr.2011.08.012 [doi]

Effect of polymer structure on micelles formed between siRNA and cationic block copolymer comprising thiols and amidines.

Rho kinase regulates the survival and transformation of cells bearing oncogenic forms of KIT, FLT3, and BCR-ABL. LID - 10.1016/j.ccr.2011.07.016 [doi]

Coenzyme Q10 suppresses oxLDL-induced endothelial oxidative injuries by the modulation of LOX-1-mediated ROS generation via the AMPK/PKC/NADPH oxidase signaling pathway

HMGB1 regulates autophagy through increasing transcriptional activities of JNK and ERK in human myeloid leukemia cells.

Quercetin induces protective autophagy in gastric cancer cells: involvement of Akt-mTOR- and hypoxia-induced factor 1α-mediated signaling.

Current progress of siRNA/shRNA therapeutics in clinical trials.

Cooperative control of tumor suppressor genes by a network of oncogenic microRNAs.

RNA-mediated silencing in Algae: biological roles and tools for analysis of gene function.

Insulin receptor substrate 2 and FoxO3a signalling are involved in E-cadherin expression and transforming growth factor-β1-induced repression in kidney epithelial cells.

Molecular dynamics simulation and binding energy calculation for estimation of oligonucleotide duplex thermostability in RNA-based therapeutics.

Involvement of endoplasmic stress protein C/EBP homologous protein in arteriosclerosis acceleration with augmented biological stress responses.

Genome-wide RNAi screens identify genes required for Ricin and PE intoxications.

Rb and p130 control cell cycle gene silencing to maintain the postmitotic phenotype in cardiac myocytes.

Dual blockade of PKA and NF-κB inhibits H2 relaxin-mediated castrate-resistant growth of prostate cancer sublines and induces apoptosis.