Latest papers

[Construction of GCV-specific hammerhead ribozyme recombinant vector of pyruvate kinase in Giardia lamblia].

Ancient machinery embedded in the contemporary ribosome.

Involvement of 1,25D3-MARRS (membrane associated, rapid response steroid-binding), a novel vitamin D receptor, in growth inhibition of breast cancer cells.

The emergence of ribozymes synthesizing membrane components in RNA-based protocells.

Multiple native states reveal persistent ruggedness of an RNA folding landscape.

Extracellular production of an RNA aptamer by ribonuclease-free marine bacteria harboring engineered plasmids: a proposal for industrial RNA drug production.

Autocatalysis and organocatalysis with synthetic structures.

Shaping RNA structures with metal ions and metal ion complexes.

RNA as a drug target: recent patents on the catalytic activity of trans-splicing ribozymes derived from group I intron RNA.

RNA therapeutics: function, design, and delivery. Preface.

Knocking down gene expression with dendritic vectors.

The application of ribozymes and DNAzymes in muscle and brain.

Hammerhead ribozymes: true metal or nucleobase catalysis? Where is the catalytic power from?

Quantifying the relationship between sequence and three-dimensional structure conservation in RNA.

The identity of the nucleophile substitution may influence metal interactions with the cleavage site of the minimal hammerhead ribozyme.

Conditional RNA interference mediated by allosteric ribozyme.

Ribozyme to TGF-beta1 mRNA abrogates immunosuppressive effects of human colorectal adenocarcinoma HRT-18 cells in vitro and in vivo.

Identification and characterization of a highly efficient anti-HIV pol hammerhead ribozyme.

Origin of life on earth.

Single-atom imino substitutions at A9 and A10 reveal distinct effects on the fold and function of the hairpin ribozyme catalytic core.