Latest papers

Coexpression of the Type 2 Diabetes Susceptibility Gene Variants KCNJ11 E23K and ABCC8 S1369A Alter the ATP and Sulfonylurea Sensitivities of the ATP-Sensitive K+ Channel

Analytical method for simultaneously measuring ex vivo drug receptor occupancy and dissociation rate: Application to (R)-dimethindene occupancy of central histamine H₁ receptors

Increased uncoupling protein (UCP) activity in Drosophila insulin-producing neurons attenuates insulin signaling and extends lifespan.

Kir6.2 Variant E23K Increases ATP-Sensitive K+ Channel Activity and Is Associated With Impaired Insulin Release and Enhanced Insulin Sensitivity in Adults With Normal Glucose Tolerance

WNK4 diverts the thiazide-sensitive NaCl cotransporter to the lysosome and stimulates AP-3 interaction.

Semi-automated unidirectional sequence analysis for mutation detection in a clinical diagnostic setting.

Development of Multiplexed Microarray Binding Assays for High-Throughput Drug Discovery

The genetic basis of congenital hyperinsulinism

[ATP-sensitive potassium channel and its cardiovascular protection effects].

[Significance of imaging biomarkers in exploratory clinical trials].

Impact of Sur1 gene inactivation on the morphology of mouse pancreatic endocrine tissue

Genetic variations in the pancreatic ATP-sensitive potassium channel, beta-cell dysfunction, and susceptibility to type 2 diabetes.

Update of mutations in the genes encoding the pancreatic beta-cell K(ATP) channel subunits Kir6.2 (KCNJ11) and sulfonylurea receptor 1 (ABCC8) in diabetes mellitus and hyperinsulinism.

Effects of ATP-sensitive potassium channels on the expression of P21, P27 and leptin.

Glibenclamide reduces inflammation, vasogenic edema, and caspase-3 activation after subarachnoid hemorrhage.

Review. SUR1: a unique ATP-binding cassette protein that functions as an ion channel regulator

Impact of plasma-protein binding on receptor occupancy: an analytical description.

[Nuclear receptors and metabolism of xenobiotics].

Meeting review: a summary of the Label-Free Summit.

Nitric oxide activates ATP-sensitive potassium channels in mammalian sensory neurons: action by direct S-nitrosylation.