Latest papers

Spatial and temporal down-regulation of transgene expression using the TRSID-silencer in mice: application to Prnp.

Splicing regulation: from a parts list of regulatory elements to an integrated splicing code.

Inactivation of a human kinetochore by specific targeting of chromatin modifiers.

Nucleoprotein structure of the CD4 locus: implications for the mechanisms underlying CD4 regulation during T cell development.

CD4-CD8 lineage commitment is regulated by a silencer element at the ThPOK transcription-factor locus.

Identification of the RA response element and transcriptional silencer in human alphaCaMKII promoter.

Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development.

Conversion of a replication origin to a silencer through a pathway shared by a Forkhead transcription factor and an S phase cyclin.

The role of Polycomb-group response elements in regulation of engrailed transcription in Drosophila.

Pre-mRNA secondary structures influence exon recognition.

Antagonistic interactions between Ikaros and the chromatin remodeler Mi-2beta determine silencer activity and Cd4 gene expression.

The "alternative" choice of constitutive exons throughout evolution.

Effects of triethylene tetraamine on the G-quadruplex structure in the human c-myc promoter.

The study of sequence configuration and functional impact of the (AC)n(AT)xTy motif in human beta-globin gene promoter.

Seemingly neutral polymorphic variants may confer immunity to splicing-inactivating mutations: a synonymous SNP in exon 5 of MCAD protects from deleterious mutations in a flanking exonic splicing enhancer.

A CTCF-binding silencer regulates the imprinted genes AWT1 and WT1-AS and exhibits sequential epigenetic defects during Wilms' tumourigenesis.

Apple chlorotic leaf spot virus 50 kDa movement protein acts as a suppressor of systemic silencing without interfering with local silencing in Nicotiana benthamiana.

[MiRNA--new mechanisms of gene expression control]

Searching for splicing motifs.

Comprehensive characterization of the cis-regulatory code responsible for the spatio-temporal expression of olSix3.2 in the developing medaka forebrain.