Latest papers

Identical kinetics of human erythrocyte and muscle acetylcholinesterase with respect to carbamate pre-treatment, residual activity upon soman challenge and spontaneous reactivation after withdrawal of the inhibitors.

Nerve agents: implications for anesthesia providers.

Resveratrol induces catalytic bioscavenger paraoxonase 1 expression and protects against chemical warfare nerve agent toxicity in human cell lines.

Acyclic phosphonate nucleotides and human adenylate kinases: impact of a borano group on alpha-P position.

Binding and hydrolysis of soman by human serum albumin.

Anticonvulsant efficacy of drugs with cholinergic and/or glutamatergic antagonism microinfused into area tempestas of rats exposed to soman.

pH-dependent interactions of indinavir and lipids in nanoparticles and their ability to entrap a solute.

Tenocyclidine treatment in soman-poisoned rats--intriguing results on genotoxicity versus protection.

Glutamate receptor pathology is present in the hippocampus following repeated sub-lethal soman exposure in the absence of spatial memory deficits.

Modifications to the organophosphorus nerve agent-protein adduct refluoridation method for retrospective analysis of nerve agent exposures.

The organophosphate-induced acute-phase response is characterized by synthesis of alpha 1-acid glycoprotein that exhibits an immunomodulatory effect.

[The development of neurotoxic agents as chemical weapons during the National Socialist period in Germany]

Biomarkers of low-level exposure to soman vapor: comparison of fluoride regeneration to acetylcholinesterase inhibition.

Quantification of organophosphorus nerve agent metabolites using a reduced-volume, high-throughput sample processing format and liquid chromatography-tandem mass spectrometry.

A gas chromatographic-mass spectrometric approach to examining stereoselective interaction of human plasma proteins with soman.

Gender difference in the miotic potency of soman vapor in rats.

Validation and application of a GC-MS method for determining soman concentration in rat plasma following low-level vapor exposure.

Aging pathways for organophosphate-inhibited human butyrylcholinesterase, including novel pathways for isomalathion, resolved by mass spectrometry.

Muscarinic receptor dysfunction induced by exposure to low levels of soman vapor.

Comparison of reactivating and therapeutic efficacy of two salts of the oxime HI-6 against tabun, soman and cyclosarin in rats.