Latest papers

A systematic review and economic evaluation of the clinical effectiveness and cost-effectiveness of aldosterone antagonists for postmyocardial infarction heart failure.

Hypertension: spironolactone and resistant hypertension.

Impact of aldosterone receptor blockade compared with thiazide therapy on sympathetic nervous system function in geriatric hypertension.

Everything old is new again: spironolactone and metformin in the treatment of acne.

Rapid reversal of left ventricular hypertrophy and intracardiac volume overload in patients with resistant hypertension and hyperaldosteronism: a prospective clinical study.

Randomized, double-blind, multicenter, placebo-controlled study evaluating the effect of aldosterone antagonism with eplerenone on ventricular remodeling in patients with mild-to-moderate heart failure and left ventricular systolic dysfunction.

Aldosterone stimulates the proliferation of uterine leiomyoma cells.

Mineralocorticoid receptor antagonism prevents hedonic deficits induced by a chronic sodium appetite.

[Effect of spironolactone on the expression of Toll-like receptor 4 in renal tubular epithelia cells exposed to high glucose].

Hirsutism: Diagnosis and management.

[Effect of aldosterone and its antagonist spironolactone on epithelial-mesenchymal transition of normal rat kidney epithelial cells in high glucose].

Understanding the risk of hyperkalaemia in heart failure: role of aldosterone antagonism.

[Effect of spironolactone on L-arginine/iNOS/NO pathway of aortic adventitia in spontaneously hypertensive rats].

Slow adoption of helpful heart failure drug. Many people who could benefit from spironolactone aren't getting it.

[Application of cardiac resynchronization therapy and ivabradine in a patient with chronic heart failure].

Association of aldosterone concentration and mineralocorticoid receptor genotype with potassium response to spironolactone in patients with heart failure.

Natriuretic peptides in heart failure: should therapy be guided by BNP levels?

[Preoperative and postoperative management of adrenal masses].

Cost effectiveness of eplerenone in patients with heart failure after acute myocardial infarction who were taking both ACE inhibitors and beta-blockers: subanalysis of the EPHESUS.

[Chronic kidney disease and the aldosterone/mineralocorticoid receptor system].