Latest papers

Physical properties of Tld, Sog, Tsg and Dpp protein interactions are predicted to help create a sharp boundary in Bmp signals during dorsoventral patterning of the Drosophila embryo.

Use of Bmp1/Tll1 doubly homozygous null mice and proteomics to identify and validate in vivo substrates of bone morphogenetic protein 1/tolloid-like metalloproteinases.

Mammalian tolloid metalloproteinase, and not matrix metalloprotease 2 or membrane type 1 metalloprotease, processes laminin-5 in keratinocytes and skin.

Isolation of connective-tissue-specific genes involved in Xenopus intestinal remodeling: thyroid hormone up-regulates Tolloid/BMP-1 expression.

Proteinases of the bone morphogenetic protein-1 family convert procollagen VII to mature anchoring fibril collagen.

Dorsoventral patterning in the zebrafish: bone morphogenetic proteins and beyond.

Biphasic activation of the BMP pathway patterns the Drosophila embryonic dorsal region.

Brinker is a sequence-specific transcriptional repressor in the Drosophila embryo.

SpSoxB1 serves an essential architectural function in the promoter SpAN, a tolloid/BMP1-related gene.

Bone morphogenetic protein-1 processes probiglycan.

Pattern formation: a new twist to BMP signalling.

Identification by differential display of a chicken tolloid-related metalloprotease specifically expressed in the caudal notochord.

Cloning of the chick BMP1/Tolloid cDNA and expression in skeletal tissues.

Processing of the Drosophila Sog protein creates a novel BMP inhibitory activity.

Structure and function of procollagen C-proteinase (mTolloid) domains determined by protease digestion, circular dichroism, binding to procollagen type I, and computer modeling.

Expression of chick BMP-1/Tolloid during patterning of the neural tube and somites.

Mammalian BMP-1/Tolloid-Related Metalloproteinases, Including Novel Family Member Mammalian Tolloid-Like 2, Have Differential Enzymatic Activities and Distributions of Expression Relevant to Patterning and Skeletogenesis

The role of tolloid/mini fin in dorsoventral pattern formation of the zebrafish embryo.

The mammalian Tolloid-like 1 gene, Tll1, is necessary for normal septation and positioning of the heart.

Local inhibition and long-range enhancement of Dpp signal transduction by Sog.