Latest papers

Hydrogen-bonding properties of galanthamine: an investigation through crystallographic database observations and computational chemistry.

Synthesis and characterization of 125I-alpha-conotoxin ArIB[V11L;V16A], a selective alpha7 nicotinic acetylcholine receptor antagonist.

Fluorescent agonists for the Torpedo nicotinic acetylcholine receptor.

Assaying small-molecule-receptor interactions by continuous flow competitive displacement chromatography/mass spectrometry.

Biophysical and ion channel functional characterization of the Torpedo californica nicotinic acetylcholine receptor in varying detergent-lipid environments.

Induced-fit or preexisting equilibrium dynamics? Lessons from protein crystallography and MD simulations on acetylcholinesterase and implications for structure-based drug design.

Lipid composition alters drug action at the nicotinic acetylcholine receptor.

Atrial fibrillation in a commercial diver.

Pixantrone (BBR2778) reduces the severity of experimental autoimmune myasthenia gravis in Lewis rats.

Epibatidine binds to four sites on the Torpedo nicotinic acetylcholine receptor.

Functional consequences of various leucine mutations in the M3/M4 loop of the Na+,K +-ATPase alpha-Subunit.

Structural answers and persistent questions about how nicotinic receptors work.

Tooth reorientation affects tooth function during prey processing and tooth ontogeny in the lesser electric ray, Narcine brasiliensis.

Gating at the mouth of the acetylcholine receptor channel: energetic consequences of mutations in the alphaM2-cap.

Irreversible thermal denaturation of Torpedo californica acetylcholinesterase

Immunolocalization of 3beta-HSD and 17beta-HSD in the testis of the spotted ray Torpedo marmorata.

Acetylcholine receptor gating: movement in the alpha-subunit extracellular domain.

Acetylcholine receptor gating at extracellular transmembrane domain interface: the cys-loop and M2-M3 linker.

Acetylcholine receptor gating at extracellular transmembrane domain interface: the pre-M1 linker.

Use of a 'caged' analogue to study the traffic of choline within acetylcholinesterase by kinetic crystallography.