Latest papers

Bovine viral diarrhea virus non-structural protein 5A interacts with NIK- and IKKbeta-binding protein.

Inhibition of hepatitis C virus replication by a specific inhibitor of serine-arginine-rich protein kinase.

Adenovirus L4-22K stimulates major late transcription by a mechanism requiring the intragenic late-specific transcription factor-binding site.

PSI-7851, a pronucleotide of beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine monophosphate, is a potent and pan-genotype inhibitor of hepatitis C virus replication.

Polo-like kinase 1 is involved in hepatitis C virus replication by hyperphosphorylating NS5A.

SARS Coronavirus Unique Domain: Three-Domain Molecular Architecture in Solution and RNA Binding

Regulation of PKR by HCV IRES RNA: Importance of Domain II and NS5A

Dimerization of the hepatitis C virus nonstructural protein 4B depends on the integrity of an aminoterminal basic leucine zipper.

Practical evaluation of a mouse with chimeric human liver model for hepatitis C virus infection using an NS3-4A protease inhibitor.

HCV NS5B polymerase inhibitors.

The crystal structure of porcine reproductive and respiratory syndrome virus nonstructural protein Nsp1beta reveals a novel metal-dependent nuclease.

Species-specific contribution of the four C-terminal amino acids of influenza A virus NS1 protein to virulence.

Rotaviruses associate with cellular lipid droplet components to replicate in viroplasms, and compounds disrupting or blocking lipid droplets inhibit viroplasm formation and viral replication.

Rotavirus nonstructural protein 1 suppresses virus-induced cellular apoptosis to facilitate viral growth by activating the cell survival pathways during early stages of infection.

Conservation of HHV-6 DNA polymerase processivity factor sequence and predicted structure suggests it as a target for antiviral development.

Inhibition of Penaeus monodon densovirus replication in shrimp by double-stranded RNA.

Dengue virus replicons: production of an interserotypic chimera and cell lines from different species, and establishment of a cell-based fluorescent assay to screen inhibitors, validated by the evaluation of ribavirin's activity.

Expanding knowledge of P3 proteins in the poliovirus lifecycle.

A plasmid encoding parts of the dengue virus E and NS1 proteins induces an immune response in a mouse model.

Effects of NS1 variants of H5N1 influenza virus on interferon induction, TNFalpha response and p53 activity.