Latest papers

Carotenoid accumulation and function in seeds and non-green tissues.

RPE65 gene delivery restores isomerohydrolase activity and prevents early cone loss in Rpe65-/- mice.

C/EBPalpha-dependent induction of glutathione S-transferase zeta/maleylacetoacetate isomerase (GSTzeta/MAAI) expression during the differentiation of mouse fibroblasts into adipocytes.

Development of a versatile reporter assay for studies of retinol uptake and metabolism in vivo.

Domain swapping between Enterococcus faecalis FabN and FabZ proteins localizes the structural determinants for isomerase activity.

RPE65 is the isomerohydrolase in the retinoid visual cycle.

The retinal G protein-coupled receptor (RGR) enhances isomerohydrolase activity independent of light.

Rpe65 is the retinoid isomerase in bovine retinal pigment epithelium.

Mole quantity of RPE65 and its productivity in the generation of 11-cis-retinal from retinyl esters in the living mouse eye.

Functional identification of novel genes involved in the glutathione-independent gentisate pathway in Corynebacterium glutamicum.

Positively charged retinoids are potent and selective inhibitors of the trans-cis isomerization in the retinoid (visual) cycle.

Cis-trans isomerase gene in psychrophilic Pseudomonas syringae is constitutively expressed during growth and under conditions of temperature and solvent stress.

Formation of trans fatty acids is not involved in growth-linked membrane adaptation of Pseudomonas putida.

Analysis in vitro of the enzyme CRTISO establishes a poly-cis-carotenoid biosynthesis pathway in plants.

Carbon isotope fractionation during cis-trans isomerization of unsaturated fatty acids in Pseudomonas putida.

Mice deficient in glutathione transferase zeta/maleylacetoacetate isomerase exhibit a range of pathological changes and elevated expression of alpha, mu, and pi class glutathione transferases.

Genetic manipulation of carotenoid biosynthesis in the green sulfur bacterium Chlorobium tepidum.

Is peptide bond cis/trans isomerization a key stage in the chemo-mechanical cycle of motor proteins?

Molecular logic of 11-cis-retinoid biosynthesis in a cone-dominated species.

The cis–trans isomerase of unsaturated fatty acids in Pseudomonas and Vibrio: biochemistry, molecular biology and physiological function of a unique stress adaptive mechanism