Latest papers

Combined rho kinase and renin-angiotensin system inhibition: a new therapeutic perspective for renal and cardiovascular remodeling.

Tetrahydroisoquinoline derivatives as highly selective and potent Rho kinase inhibitors.

A novel biased allosteric compound inhibitor of parturition selectively impedes the prostaglandin F2alpha-mediated Rho/ROCK signaling pathway.

Lysophosphatidic acid signals through multiple receptors in osteoclasts to elevate cytosolic calcium concentration, evoke retraction, and promote cell survival.

8,9-Epoxyeicosatrienoic acid analog protects pulmonary artery smooth muscle cells from apoptosis via ROCK pathway

Revisited and revised: is RhoA always a villain in cardiac pathophysiology?

S1P2 receptor-dependent Rho-kinase activation mediates vasoconstriction in the murine pulmonary circulation induced by sphingosine 1-phosphate.

Printing a tissue: a new engineering strategy for cardiovascular regeneration.

Therapeutic angiogenesis by implantation of a capillary structure constituted of human adipose tissue microvascular endothelial cells.

Rho-kinase mediates lysophosphatidic acid-induced IL-8 and MCP-1 production via p38 and JNK pathways in human endothelial cells.

Rho kinase activation and ROS production contributes to the cooling enhanced contraction in cutaneous equine digital veins.

Osteoprotegerin induces cytoskeletal reorganization and activates FAK, Src, and ERK signaling in endothelial cells.

Analysis of responses to the Rho-kinase inhibitor Y-27632 in the pulmonary and systemic vascular bed of the rat.

The effects of 1,25-dihydroxyvitamin D3 on colon cancer cells depend on RhoA-ROCK-p38MAPK-MSK signaling.

Cytoskeleton plays a dual role of activation and inhibition in myelin and zymosan phagocytosis by microglia.

TRE17/USP6 oncogene translocated in aneurysmal bone cyst induces matrix metalloproteinase production via activation of NF-kappaB.

Clonal expansion of human pluripotent stem cells on gelatin-coated surface

AMP-activated protein kinase induces actin cytoskeleton reorganization in epithelial cells

Melatonin sensitizes human myometrial cells to oxytocin in a protein kinase C alpha/extracellular-signal regulated kinase-dependent manner.

Amiloride reduces portal hypertension in rat liver cirrhosis.