1. Staphylococcus epidermidis and biofilm-associated neutrophils in chronic rhinosinusitis. A pilot study.

    International Journal of Experimental Pathology 96(6):378 (2015) PMID 26765504 PMCID PMC4744824

    A key role of bacterial biofilm in the pathogenesis of chronic rhinosinusitis (CRS) with (CRSwNP) and without nasal polyps (CRSsNP) is commonly accepted. However, the impact of some bacterial species isolated from inflamed sinus mucosa on biofilm formation is unclear. In particular, the role of ...
  2. Study on inhibitory activity of chitosan-based materials against biofilm producing Pseudomonas aeruginosa strains.

    Journal of Biomaterials Applications 30(3):269 (2015) PMID 25855683

    Six antibiotic-resistant Pseudomonas aeruginosa strains, isolated from chronic diabetic foot infections, were chosen for studying the influence of different chitosan-based materials: chitosan solution and chitosan submicroparticles in both planktonic and 24 h-old biofilm-forming models. Chitosan...
  3. Visible light induced photocatalytic inactivation of bacteria by modified titanium dioxide films on organic polymers.

    Photochemical & Photobiological Sciences 14(3):514 (2015) PMID 25254352

    Commercially available polypropylene foil was pretreated with a low temperature oxygen plasma and covered with a thin film of nanocrystalline titanium dioxide by dip coating. The films were then photosensitized by titanium(IV) surface charge transfer complexes formed by impregnation with catecho...
  4. Taurine Haloamines and Biofilm. Part I: Antimicrobial Activity of Taurine Bromamine and Chlorhexidine Against Biofilm Forming Pseudomonas aeruginosa.

    Advances in Experimental Medicine and Biology 803:121 (2015) PMID 25833493

  5. Efficacy and safety of a vaginal medicinal product containing three strains of probiotic bacteria: a multicenter, randomized, double-blind, and placebo-controlled trial.

    Drug Design, Development and Therapy 9:5345 (2015) PMID 26451088 PMCID PMC4590344

    The main objective of this study was to evaluate whether vaginal administration of probiotic Lactobacillus results in their colonization and persistence in the vagina and whether Lactobacillus colonization promotes normalization and maintenance of pH and Nugent score. The study was a multicenter...
  6. Distinct effects of Lactobacillus plantarum KL30B and Escherichia coli 3A1 on the induction and development of acute and chronic inflammation.

    Central European Journal of Immunology 40(4):420 (2015) PMID 26862305 PMCID PMC4737739

    Enteric bacteria are involved in the pathogenesis of ulcerative colitis. In experimental colitis, a breakdown of the intestinal epithelial barrier results in inflow of various gut bacteria, induction of acute inflammation and finally, progression to chronic colitis. In the present study we compa...
  7. Supplementation of standard antibiotic therapy with oral probiotics for bacterial vaginosis and aerobic vaginitis: a randomised, double-blind, placebo-controlled trial.

    BMC Women's Health 15(1):115 (2015) PMID 26635090 PMCID PMC4669640

    This multicentre, randomised, double-blind, placebo-controlled trial was performed to determine whether the use of oral probiotic preparation (prOVag®) containing three Lactobacillus strains together with standard metronidazole treatment and also targeted antibiotic treatment (following the fail...
  8. The structure and immunoreactivity of exopolysaccharide isolated from Lactobacillus johnsonii strain 151.

    Carbohydrate Research 378:148 (2013) PMID 23787056

    The exopolysaccharide (EPS) structure from Lactobacillus johnsonii strain 151 isolated from the intestinal tract of mice was investigated. Sugar and methylation analyses together with (1)H and (13)C NMR spectroscopy, including two-dimensional (1)H,(1)H COSY, TOCSY, NOESY, and (1)H,(13)C HSQC, HM...
  9. Virulence factors of Enterococcus strains isolated from patients with inflammatory bowel disease.

    World Journal of Gastroenterology 19(23):3562 (2013) PMID 23801857 PMCID PMC3691038

    To determine the features of Enterococcus that contribute to the development and maintenance of the inflammatory process in patients with inflammatory bowel disease (IBD). Multiplex polymerase chain reaction (PCR) was applied to assess the presence of genes that encode virulence factors [surface...
  10. A high-throughput method for the quantification of iron saturation in lactoferrin preparations.

    Analytical and Bioanalytical Chemistry 405(15):5191 (2013) PMID 23604471 PMCID PMC3656221

    Lactoferrin is considered as a part of the innate immune system that plays a crucial role in preventing bacterial growth, mostly via an iron sequestration mechanism. Recent data show that bovine lactoferrin prevents late-onset sepsis in preterm very low birth weight neonates by serving as an iro...
  11. Bacterial infections of the lower genital tract in fertile and infertile women from the southeastern Poland.

    Ginekologia polska 84(5):352 (2013) PMID 23819400

    The objective of the study was to investigate the detection rates of Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma urealyticum, Gardnerella vaginalis, Escherichia coli, Streptococcus agalactiae and Enterococcus faecalis, showing no clinical s...
  12. Antibiotic resistance: a "dark side" of biofilm‑associated chronic infections.

    Polskie archiwum medycyny wewnetrznej 123(6):309 (2013) PMID 23828150

    Bacteria may exist in nature in a planktonic form or in biofilms that allow bacteria to survive in an unfriendly microenvironment. Biofilm is a structured community of bacteria hidden in a self-produced polymeric matrix of polysaccharides, proteins, and extracellular DNA. Biofilm-growing bacteri...
    PDF not found
  13. Influence of taurine haloamines (TauCl and TauBr) on the development of Pseudomonas aeruginosa biofilm: a preliminary study.

    Advances in Experimental Medicine and Biology 775:269 (2013) PMID 23392942

    Biofilms are consortia of microorganisms (sessile cells) that form on various surfaces including mucosal membranes or teeth. Bacterial biofilms cause many human infections such as chronic sinusitis, acne vulgaris, periodontal diseases, and chronic wounds. These infections are persistent as they ...
  14. Adherence of group B streptococci to human rectal and vaginal epithelial cell lines in relation to capsular polysaccharides as well as alpha-like protein genes - pilot study.

    Polish Journal of Microbiology 62(1):85 (2013) PMID 23829083

    Streptococcus agalactiae (Group B Streptococci, GBS) constitutes a risk factor for infections of the newborns born by colonized mothers. The adherence of GBS to epithelial cells has been proved to be an important factor in the colonization of mucus membranes of both human rectum and vagina. The ...
  15. Possible role of Escherichia coli in propagation and perpetuation of chronic inflammation in ulcerative colitis.

    BMC Gastroenterology 13:61 (2013) PMID 23566070 PMCID PMC3637091

    This study investigated a possible role of Escherichia coli in propagation and perpetuation of the chronic inflammation in ulcerative colitis (UC). The lesions of UC are located superficially on the rectal and/or colonic mucosa. It is suggested that the commensal bacteria of the digestive tract ...
  16. Studies on the effects of probiotic Lactobacillus mixture given orally on vaginal and rectal colonization and on parameters of vaginal health in women with intermediate vaginal flora.

    European Journal of Obstetrics & Gynecology and... 163(2):210 (2012) PMID 22721635

    The vaginal microflora is composed of many bacterial species and plays a major role in maintaining the balance of this complex environment. This study was conducted in order to assess the degree and persistence of the colonization of vaginal epithelium by strains from an orally administered mixt...
  17. Laboratory diagnostics of renal function in an experimental model of ascending pyelonephritis with high-virulent Escherichia coli.

    Folia medica Cracoviensia 52(1-2):25 (2012) PMID 23697213

    Urinary tract infections (UTI) are caused in 95% of cases by bacteria--E. coli. UTIs usually are limited to the lower urinary tract, but it may also evolve into pyelonephritis and acute kidney injury. The aim of this study was the laboratory evaluation of renal function in an experimental model ...
  18. Horizontal distribution of the fecal microbiota in adolescents with inflammatory bowel disease.

    Journal of Pediatric Gastroenterology and Nutri... 54(1):20 (2012) PMID 21788912

    The commensal microbiota of the gastrointestinal tract plays an important role in the pathogenesis of inflammatory bowel disease. We examined the horizontal structure of the fecal microbiota in the colon in adolescents with Crohn disease or ulcerative colitis and a control group. Fecal samples w...
  19. Structural studies of the exopolysaccharide consisting of a nonasaccharide repeating unit isolated from Lactobacillus rhamnosus KL37B.

    Carbohydrate Research 346(18):2926 (2011) PMID 22063501

    A novel structure of exopolysaccharide from the lactic acid bacteria (LAB) Lactobacillus rhamnosus KL37B, from the human intestinal flora, is described. During the structural investigation of the exopolysaccharide it was found that the repeating unit is a nonasaccharide, which is the largest rep...
  20. [Antibiotic resistance of Gardnerella vaginalis isolated from cases of bacterial vaginosis].

    Ginekologia polska 82(12):900 (2011) PMID 22384625

    Gardnerella vaginalis is one of the dominant etiological factors related to bacterial vaginosis. Literature offers a growing number of reports revealing there appear Gardnerella vaginalis strains increasingly resistant to metronidazole. The aim of this study was to determine the susceptibility o...