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  1. Preeclampsia as a risk factor for diabetes: a population-based cohort study.
    Denice S Feig, Baiju R Shah, ... Gillian L Booth

    PLoS Med 10(4):e1001425 (2013) PMID 23610560

    We performed a population-based, retrospective cohort study for 1,010,068 pregnant women who delivered in Ontario, Canada between April 1994 and March 2008. Women were categorized as having PEC alone (n = 22,933), GH alone (n = 27,605), GDM alone (n = 30,852), GDM+PEC (n = 1,476), GD...
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  2. Grand challenges in global mental health: integration in research, policy, and practice.
    Pamela Y Collins, Thomas R Insel, ... Yvonne T Maddox

    PLoS Med 10(4):e1001434 (2013) PMID 23637578

    In the first article of a five-part series providing a global perspective on integrating mental health, Pamela Collins and colleagues set the scene for why mental health care should be combined with priority programs on maternal and child health, non-communicable diseases, and HIV, a...
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  3. Excess Long-Term Mortality following Non-Variceal Upper Gastrointestinal Bleeding: A Population-Based Cohort Study.
    Colin John Crooks, Timothy Richard Card, and Joe West

    PLoS Med 10(4):e1001437 (2013) PMID 23637580

    We investigated the excess causes of death in individuals after a non-variceal bleed compared with deaths in a matched sample of the general population. Linked longitudinal data from the English Hospital Episodes Statistics (HES) data, General Practice Research Database (GPRD), and O...
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  4. Fine particulate air pollution and the progression of carotid intima-medial thickness: a prospective cohort study from the multi-ethnic stud...
    Sara D Adar, Lianne Sheppard, ... Joel D Kaufman

    PLoS Med 10(4):e1001430 (2013) PMID 23637576

    We examined associations between the progression of the intima-medial thickness (IMT) of the common carotid artery, as an indicator of atherosclerosis, and long-term PM2.5 concentrations in participants from the Multi-Ethnic Study of Atherosclerosis (MESA). MESA, a prospective cohort...
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  5. Implementation and scale-up of psycho-trauma centers in a post-conflict area: a case study of a private-public partnership in northern Ugand...
    Etheldreda Nakimuli-Mpungu, Stephen Alderman, ... Seggane Musisi

    PLoS Med 10(4):e1001427 (2013) PMID 23610562

    As one article in an ongoing series on Global Mental Health Practice, Etheldreda Nakimuli-Mpungu and colleagues describe a private-public partnership that implemented and scaled psycho-trauma centers in Northern Uganda.
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  6. Prophylactic perioperative sodium bicarbonate to prevent acute kidney injury following open heart surgery: a multicenter double-blinded rand...
    Michael Haase, Anja Haase-Fielitz, ... Sean M Bagshaw

    PLoS Med 10(4):e1001426 (2013) PMID 23610561

    We tested whether prophylactic bicarbonate-based infusion reduces the incidence of acute kidney injury and tubular damage in patients undergoing open heart surgery. In a multicenter, double-blinded (patients, clinical and research personnel), randomized controlled trial we enrolled 3...
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  7. Big data opportunities for global infectious disease surveillance.
    Simon I Hay, Dylan B George, ... John S Brownstein

    PLoS Med 10(4):e1001413 (2013) PMID 23565065

    Simon Hay and colleagues discuss the potential and challenges of producing continually updated infectious disease risk maps using diverse and large volume data sources such as social media.
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  8. Cinacalcet in patients with chronic kidney disease: a cumulative meta-analysis of randomized controlled trials.
    Suetonia C Palmer, Ionut Nistor, ... Giovanni F M Strippoli

    PLoS Med 10(4):e1001436 (2013) PMID 23637579

    We conducted a systematic review and meta-analysis to summarize the benefits and harms of calcimimetic therapy in adults with CKD and used cumulative meta-analysis to identify how evidence for calcimimetic treatment has developed in this clinical setting. Cochrane and Embase database...
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  9. Industry use of evidence to influence alcohol policy: a case study of submissions to the 2008 Scottish government consultation.
    Jim McCambridge, Ben Hawkins, and Chris Holden

    PLoS Med 10(4):e1001431 (2013) PMID 23630458

    Jim McCambridge and colleagues analyze industry submissions to a Scottish Government consultation on whole-population approaches to alcohol policy.
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  10. Life expectancies of South african adults starting antiretroviral treatment: collaborative analysis of cohort studies.
    Leigh F Johnson, Joel Mossong, ... International Epidemiologic Databases to Evaluate AIDS Southern Africa (IeDEA-SA) Collaboration

    PLoS Med 10(4):e1001418 (2013) PMID 23585736

    We aimed to estimate the life expectancy of patients starting ART in South Africa and compare it with that of HIV-negative adults. Data were collected from six South African ART cohorts. Analysis was restricted to 37,740 HIV-positive adults starting ART for the first time. Estimates...
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